Understanding asthma phenotypes: the World Asthma Phenotypes (WASP) international collaboration
نویسندگان
چکیده
منابع مشابه
Asthma phenotypes
Currently, categorization based on cluster analysis by objectively grasping the diversity of pathology is being conducted and the diversity of asthma is being categorized as phenotypes. Clinically, there is categorization based on aging and on allergic diathesis which is clinically useful; however, it has not, up to now, come to the point of selection based on phenotype. Subsequently, what is d...
متن کاملPhenotyPes in AsthmA
Asthma is a heterogeneous disorder presenting with many phenotypes. Improved phenotypic characterization is necessary for linkage of specific genotypes with clinical disease manifestations. Since genotypic and phenotypic heterogeneity are inherent in asthma, patients presenting with different asthma phenotypes may need tailored therapies. The advent of targeted therapies for asthma and clinical...
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PURPOSE OF REVIEW Asthma is a phenotypically heterogeneous disorder and, over the years, many different clinical subtypes of asthma have been described. A precise definition of asthma phenotypes is now becoming more and more important, not only for a better understanding of pathophysiologic mechanisms, but in particular to ascertain the specific genes associated with these phenotypes. RECENT ...
متن کاملSubclinical phenotypes of asthma.
PURPOSE OF REVIEW Asthma is a heterogeneous disease. Identification of specific subphenotypes of asthma may further our understanding of pathophysiology and treatment response, leading to the better targeting of both existing and novel antiasthma therapies. An accurate and comprehensive clinicopathological classification system therefore remains an important priority for asthma research. The pr...
متن کاملClinical asthma phenotypes in the real world: opportunities and challenges
Asthma is a common, chronic and heterogeneous syndrome, affecting people of all ages, all races and both sexes. It may range from mild disease with barely noticeable symptoms, to very severe disease with constant symptoms that greatly hinder the life of the patient. Guidelines issued by various medical societies provide guidance on how to diagnose and manage asthmatic patients. It is now increa...
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ژورنال
عنوان ژورنال: ERJ Open Research
سال: 2018
ISSN: 2312-0541
DOI: 10.1183/23120541.00013-2018